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  • BioRestorative Reports Positive Phase 2 Data for BRTX-100 in Chronic Lumbar Disc Disease

    BioRestorative Therapies Reports Positive  Phase 2 Blinded Data for BRTX-100 Demonstrating Meaningful Improvements in Pain and Function in Chronic Lumbar Disc Disease

    MELVILLE, N.Y., March 30, 2026 — BioRestorative Therapies, Inc. (“BioRestorative,” “BRTX,” or the “Company”) (Nasdaq:BRTX), a late-stage clinical regenerative medicine company focused on stem cell-based therapies and products, today announced blinded data from its Phase 2 clinical trial evaluating hypoxic-cultured mesenchymal stem cells for the treatment of chronic lumbar disc disease, with 50% or more of treated patients reporting improvements >50% across key pain and functional outcome measures and no adverse events related to dose-limiting toxicities.  Importantly, the Phase 2 study efficacy endpoint is a greater than a 30% improvement in both the Visual Analog Scale (VAS) and Oswestry Disability Index (ODI) at 52 weeks, which is the minimum improvement needed to meet clinical efficacy success. Chronic lumbar disc disease is a leading cause of chronic lower back pain and disability, affecting millions of patients globally and representing a significant unmet need for non-surgical regenerative therapies.

    These data were presented at the 2026 Orthopaedic Research Society Annual Meeting on March 28, 2026 at the Charlotte Convention Center in Charlotte, North Carolina. The Company delivered these data in a presentation titled, “Late-Stage Phase 2 Clinical Safety and Efficacy Data on Intradiscal Injections of Hypoxic Cultured Mesenchymal Stem Cells: Study Update.”

    “These blinded data further support the therapeutic potential of our hypoxic-cultured mesenchymal stem cell technology, with  patients demonstrating meaningful improvements across key pain and functional outcome measures,” said Lance Alstodt, BioRestorative Therapies President, Chief Executive Officer, and Chairman.  “Even with blinded data, this signal provides us with confidence in the ultimate outcome of the study, and optimism moving forward with regard to the ultimate potential for meeting a medical need that has, to date, been inadequately addressed.

    “Importantly, the results also continue to reinforce the favorable safety and tolerability profile observed to date. In addition, following our recent Type B meeting with the U.S. Food and Drug Administration, we achieved alignment on key elements of a potential Phase 3 clinical trial for BRTX-100, including primary endpoints, statistical powering assumptions, dosing strategy, and the overall development framework. The agency did not raise safety concerns and confirmed that our CMC framework is appropriate for late-stage development.

    “Taken together, these developments position the Company to transition from clinical evaluation toward registrational planning. As we move toward the planned unblinding of the Phase 2 study, we have begun preparing for the next stage of clinical development, including protocol planning and other Phase 3 readiness activities, while continuing to generate additional clinical data that may support the advancement and potential commercialization of BRTX-100,” concluded Mr. Alstodt.

    Clinically meaningful improvements in both pain and functional outcomes were observed across multiple validated pain and function measures, including the Visual Analog Scale (“VAS”), Oswestry Disability Index (“ODI”), Roland-Morris Disability Questionnaire (“RMDQ”), and Functional Rating Index (“FRI”), with responses sustained for up to two years in patients with longer-term follow-up.

    On the VAS for pain, 53.57% of patients reported greater than 50% improvement at 26 weeks (n=28), with the percentage of patients that reported greater than 50% improvement increasing to 75% at 52 weeks (n=12) and remaining 75% at 104 weeks (n=4).

    Similar improvements were observed on the ODI, a widely used measure of functional impairment associated with spinal disorders.  Blinded results from the abstract showed 53.57% of patients achieved greater than 50% improvement at 26 weeks (n=28), increasing to 74.63% of patients at 52 weeks (n=12), with 50% of patients maintaining that level of improvement at 104 weeks (n=4).

    Improvements were also observed on the RMDQ, with 57.14% of patients experiencing greater than 50% improvement at 26 weeks (n=28), 50% of patients at 52 weeks (n=12), and 75% of patients at 104 weeks (n=4).

    FRI demonstrated continued improvement over time, with 35.71% of patients achieving greater than 50% improvement at 26 weeks (n=28), increasing to 66.67% of patients at 52 weeks (n=12) and 50% of patients at 104 weeks (n=4).

    Finally, at 26 weeks (n=28) 41% of patients reported a 50% improvement in both ODI and VAS, 55% of patients achieved a 50% improvement in both ODI and VAS at 52 weeks (n=12), and at 104 weeks (n=4) 57% of patients met a 50% improvement in both ODI and VAS.

  • Tezos RWA Ecosystem Expands with Launch of Metals.io

    London, UK—30th March, 2026— Metals.io, a new application for investing in and trading tokenized commodities, is live in the Tezos ecosystem. Developed by a team at Trilitech, a London-based Tezos R&D hub, the web app unlocks access to a selection of rare-earth metals, as well as base metals and minerals that are critical to the technology sector and the AI boom. Designed from the ground up as a single entry-point to a range of tokenized assets, metals.io launches with a dedicated and user-centric web app, which enables users to search for and add a range of tokenized commodities to their portfolios. Metals.io benefits from Tezos’ smart-rollup technology, which boasts sub-50ms latency, meaning that traders on the platform enjoy near-instant transaction confirmations, giving them the critical advantage they need in this dynamic market. 

    Tezos RWA Ecosystem Expands with Launch of Metals.io

    Metals.io is launching at a pivotal moment, as demand for critical minerals and precious metals has intensified recently, driven on one hand by industrial applications and on the other by investors seeking portfolio diversification options in the face of economic uncertainty. The U.S. government’s establishment of a U.S. critical mineral reserve has led to further attention on these assets, which are essential to modern manufacturing and used in everything from smartphones to wind turbines and fighter jets. Metals.io launches with a number of these tokenized assets already live, with more to be added in the coming months. From today, visitors to the site can access xU3O8 tokenized uranium; VNX Gold (VNXAU), digital proof of ownership of allocated gold which is physically held in a high-security vault in Liechtenstein; and the RARE token from Noemon Tech, which provides transparent exposure to a diversified basket of five strategic metals selected for their critical industrial and technological value. 

    “The current rapid pace of innovation in the AI sector and several other related fields is having a knock-on effect on demand for metals and materials that are critical to these endeavors. RARE enables users to gain digital ownership of a diversified basket of strategic metals – including elements such as hafnium, rhenium, indium, neodymium oxide, and praseodymium oxide – all of which are key to modern technologies and industrial applications. The team at Trilitech has developed an incredible gateway for accessing these assets, and Metals.io is a great showcase of how the future of RWA investing is taking place on Tezos,” said Dimitrios Kavvathas, Founder of Noemon Tech Ltd.

    Metals.io uses the same underpinning technology as the uranium.io platform that launched on Etherlink, the EVM interface for Tezos, in December 2024. Uranium.io was purpose-built to minimise barriers to investing in uranium ore concentrate (U3O8), the asset that is used in nuclear reactors and could be key to powering the AI revolution. Since launching, uranium.io has played a pivotal role in bridging the multi-billion-dollar traditional commodity market with the speed and transparency of decentralized finance (DeFi), welcoming new investors who would not previously have had the opportunity to own and trade the commodity. The platform has received widespread industry recognition for these innovations, including winning the Best New Product award in the Innovation in Crypto & Web3 category at the latest Benzinga Global Fintech Awards. Now, metals.io is leveraging this successful model to facilitate access to other in-demand assets such as gold and other critical base metals.

    “Throughout the 21st century, gold has consistently proven itself as one of the world’s premier assets, delivering stability and preserving wealth when traditional markets waver. VNX Gold (VNXAU) brings this enduring value into the modern era by offering digital tokens that represent verifiable proof of ownership of allocated gold, held in high-security vaults. By combining the strength of industry-leading custodians with the transparency and immutability of blockchain technology, we provide investors with all the security of physical gold, elevated with the efficiency, divisibility, and flexibility of a digital asset, allowing gold to become a fractional and programmable asset that can participate in modern on-chain financial services. Built on the robust and energy-efficient Tezos blockchain, VNX Gold (VNXAU) is making verifiable gold ownership accessible to a new generation of investors,” said Alexander Tkachenko, CEO and Founder, VNX.

    Commenting on the launch of Metals.io, Arthur Breitman, co-founder of Tezos, said, “Commodity markets are global and indispensable, yet access to them remains fragmented and layered with intermediaries. As the AI revolution accelerates, energy and critical materials are becoming core economic constraints. Tokenization streamlines ownership and transfer of these assets at a global scale. Metals.io represents the maturation of that model, bringing essential commodities directly onto modern digital rails.”

  • Cured Nutrition Expands Best-selling Dream Gummies Line With New Strawberry Flavor

    The latest addition to CURED’s sleep and stress relief lineup arrives on the heels of a sellout launch.

     

    BOULDER, CO (March 30, 2026) – CURED Nutrition, a health and wellness brand harnessing the power of microdosed cannabinoids and functional mushrooms, today announced the launch of a strawberry flavor of its best-selling Dream Gummies. The new flavor is available now at curednutrition.com alongside the original grape.

    Dream Gummies rank among CURED’s top-selling products — and for good reason. When the line debuted in November 2025, it sold out within two weeks, signaling a growing consumer demand for credible, third-party tested sleep support. In a 1,000-person study, participants who used CURED products for seven days reported significantly reduced stress and increased feelings of calm and physical ease — making the transition to restful sleep measurably simpler.

    “Sleep is the foundation of overall health, and our 235,000+ customers trust us to support their end-of-day unwind in a clean, sustainable way. Dream was built to honor that trust,” said Joseph Sheehey, CEO and Co-Founder of CURED Nutrition.

    Dream Gummies combine a precision cannabinoid and botanical formula — CBD, CBN, and a microdose of THC, paired with valerian root, passionflower, and chamomile. The result is deep, restorative sleep without the intoxicating effects of high-dose THC or the next-day fog common to most sleep supplements.

    “Dream gummies are the perfect combo of my go-to plants for helping me fall asleep,” said Heather K., a verified user of CURED’s Dream gummies and a CURED Nutrition influencer. “Perimenopause is no joke when it comes to a good night’s sleep, and these gummies are exactly the potency I was hoping for to help my body sleep deep!” 

    You can see more of Heather’s reviews of CURED’s products on her Instagram profile, linked here: https://www.instagram.com/cleanerliving.heatherk/?hl=en

    CURED’s microdose approach uses approximately one-tenth the THC found in a standard edible — enough to deliver subtle, functional benefits like reduced stress, elevated mood, and improved quality of life, without the high. Every batch is produced in the United States and third-party tested for purity and potency.

  • Boost Milkshake Unveils ‘The New Secret of Mahi Energy – a befitting tribute to MS Dhoni & his fans

    Boost Milkshake Unveils ‘The New Secret of Mahi Energy – a befitting tribute to MS Dhoni & his fans

    Hyderabad, Mar 30: Boost Milkshake, the ready-to-drink energy beverage, launches its latest campaign “The New Secret of Mahi Energy” as a tribute to MS Dhoni aka Mahi & his millions of fans across the nation,

    For years, MS Dhoni has defined calm, resilience, and match-winning stamina. With bat or gloves, on or off fields his mere presence is enough to have an impact. No wonder, he is and will always be Thala for a reason.

    In the stands, millions of fans mirror that same energy – showing up, believing, and powering every moment with unmatched passion.

    At the heart of the idea is a simple equation: Mahi energy fuels his fans, and fans’ energy charges up the FOREVER legend in the iconic no. 7 jersey.

    Boost Milkshake becomes the common source that powers this two-way exchange – from the pitch to the stands and back again.

    From roaring stadiums to everyday fan rituals, the campaign celebrates the stamina behind fandom – the chants, the loyalty, and the belief that never fades. And it is a heartfelt tribute to each and every die-hard supporter who has stood behind Dhoni, no matter what.

    Commenting on the campaign, Rajneet Kohli, Executive Director – Foods & Beverages, HUL said “MS Dhoni’s legacy of Consistency, resilience, and energy define the spirit of Mahi and millions of Indians who show up every day and keep going. Boost Milkshake brings this spirit to life in a chilled ready to drink, great-tasting format. The campaign celebrates the idea of everyday energy — the drive that fuels moments of focus, effort, and perseverance — positioning Boost Milkshake as a simple, everyday source of energy that fits seamlessly into modern lives.”

    Bringing this alive, the campaign rolls out across key cricketing hubs with a strong outdoor presence in Mumbai, Chennai, and Guwahati, alongside collaborations with fan pages and bringing a leading Mahi superfan Sarvanan Hari on board. A dedicated Instagram handle further anchors the campaign as an always-on hub for fan stories and match-day energy.

    More than a campaign, Boost Milkshake celebrates the spirit behind the ‘Energy That Unites Mahi & his million fans’, a phenomenon where fandom becomes a force and energy, a shared identity.

    This season is dedicated to Mahi energy.

    Limitless, all powerful and felt by millions.

  • India Pharma 2026 Highlights Move from Volume to Innovation Led Growth

    New Delhi: The upcoming India Pharma 2026 is set to spotlight India’s transition from volume-driven production to an innovation-led growth model in the pharmaceutical sector.

    Industry leaders and policymakers are expected to use the platform to highlight the need for stronger research and development, advanced manufacturing, and greater global competitiveness. The focus is shifting from producing large quantities of generic medicines to developing high-value drugs, novel therapies, and cutting-edge technologies.

    Experts believe this transition is crucial for India to strengthen its position in the global pharmaceutical landscape. While the country has long been known as a major supplier of affordable medicines, the next phase of growth will depend on investments in innovation, quality, and intellectual property.

    The event will also provide an opportunity to discuss regulatory reforms, collaborations between industry and academia, and strategies to boost exports. Participants are likely to explore how emerging technologies and digital solutions can further enhance efficiency and innovation in the sector.

    With growing global demand for advanced healthcare solutions, India Pharma 2026 is expected to serve as a key platform to shape the future direction of India’s pharmaceutical industry.

  • Himachal Governor Briefs PM Modi on Key Development Initiatives

    New Delhi: Himachal Pradesh Governor Shiv Pratap Shukla met Prime Minister Narendra Modi in New Delhi to discuss a range of important initiatives and developments in the state.

    During the meeting, the Governor apprised the Prime Minister of ongoing welfare programmes, administrative priorities, and efforts aimed at strengthening infrastructure and public services in Himachal Pradesh. He also highlighted steps being taken to promote sustainable development and improve the overall quality of life for residents.

    The discussion included key sectors such as rural development, healthcare, and tourism, which continue to play a vital role in the state’s growth. The Governor shared updates on recent progress and sought continued support from the Centre for upcoming projects.

    Prime Minister Modi appreciated the efforts being made in the state and reiterated the Centre’s commitment to supporting Himachal Pradesh’s development journey. The meeting reflects ongoing coordination between the state and the Centre to ensure effective implementation of policies and programmes.

  • CCRAS Partners with AI Platform to Expand Ayurveda Research Across Languages

    New Delhi: The Central Council for Research in Ayurvedic Sciences (CCRAS) has joined hands with Anuvadini AI to make Ayurveda research more accessible to people across India by translating it into 13 languages.

    The initiative aims to bridge language barriers that often limit access to traditional knowledge, especially in a country as linguistically diverse as India. By leveraging artificial intelligence, the collaboration will enable wider dissemination of research findings, educational materials, and scientific literature related to Ayurveda.

    Officials said the move is expected to benefit students, researchers, and practitioners by allowing them to access authentic information in their native languages. It will also help bring traditional Indian medical knowledge closer to local communities, encouraging greater awareness and understanding.

    The partnership reflects a growing effort to combine technology with traditional systems of medicine, making them more inclusive and easier to engage with. By expanding the reach of Ayurveda research, CCRAS hopes to promote its relevance not just within India but also on a global stage.

  • Uttar Pradesh to Expand Anganwadi Workforce with Major Recruitment Drive

    Lucknow: Uttar Pradesh Chief Minister Yogi Adityanath has announced a large-scale recruitment drive to strengthen the state’s Anganwadi system, with plans to hire 5,000 Anganwadi workers and 60,000 helpers this year.

    The move is aimed at improving the delivery of nutrition, healthcare, and early childhood services under the Integrated Child Development Services (ICDS) scheme. Officials said the recruitment will help address staff shortages and ensure better outreach, particularly in rural and underserved areas.

    Highlighting the importance of Anganwadi centres, the Chief Minister stressed their role in supporting the health and development of children, as well as providing essential services to pregnant women and new mothers. Strengthening this network, he noted, is key to improving overall community well-being.

    The state government is expected to streamline the recruitment process to ensure transparency and timely appointments. Once completed, the expanded workforce is likely to enhance service delivery and bring greater efficiency to grassroots welfare programmes.

  • Rising Burnout in Competitive Exams Signals Urgent Need for Balanced Learning Approaches

    Rising Burnout in Competitive Exams Signals Urgent Need for Balanced Learning Approaches

    India’s intensely competitive entrance examination ecosystem spanning engineering, medical, government and management streams is increasingly confronting a deepening mental health challenge, with student burnout emerging as a critical concern. As preparation cycles grow more rigorous and prolonged, education experts are calling for a calibrated shift towards more balanced and sustainable learning practices.

    Recent data underscores the scale of the issue. According to findings cited from national-level studies, over 80 per cent of students in India report experiencing exam-related stress and anxiety, reflecting the pervasive psychological pressure embedded within the system.
    Further, a nationwide student well-being survey indicates that nearly one in five high school students rarely feels calm, motivated or emotionally secure, pointing to rising levels of disengagement and fatigue.

    Across the country, particularly in rapidly expanding education hubs in Tier 2 and Tier 3 cities, students are navigating heightened academic expectations. Extended study hours, continuous performance assessment and intense competition are contributing to elevated levels of stress, anxiety and emotional exhaustion. While access to coaching institutes and digital learning platforms has widened significantly, the corresponding focus on mental well-being continues to lag behind.

    The entrenched culture of over-preparation often characterised by exhaustive study routines and minimal recovery time—is now drawing increasing scrutiny. Students are reporting symptoms associated with burnout, including diminished motivation, sleep disturbances and heightened anxiety, raising concerns about long-term implications on both academic performance and overall health.

    In response, sections of the coaching and edtech ecosystem are gradually moving towards a more holistic, student-centric approach. There is a discernible shift towards structured and personalised learning frameworks that integrate mental health awareness, balanced schedules and efficient preparation strategies aimed at optimising outcomes without overwhelming students.

    Neeraj Kansal, Founder & CEO of Crack Academy, said, “Success in competitive examinations must not come at the cost of mental well-being. The focus today should be on smarter, structured preparation that fosters balance and resilience. Students perform best in environments that support them, rather than overwhelm them.”

    Industry observers further emphasise the role of parents and educators in mitigating this growing concern. Encouraging realistic expectations, fostering open communication and recognising consistent effort over purely outcome-driven benchmarks can significantly reduce the psychological burden on students.

    As India’s examination ecosystem evolves, mental health is set to become a defining pillar in shaping future education paradigms. The narrative is steadily shifting from purely result-oriented frameworks to more sustainable models that prioritise resilience, balance and long-term student success. 

  • Check Point at RSAC How We’re Helping Our Customers Secure their AI Transformation

    By: Jonathan Zanger, CTO

    Enterprise organizations are rapidly adopting AI tools to accelerate productivity, unlock fresh business insights, gain new competitive advantages, and drive revenue growth. But this transformation is bringing with it new and complex security challenges that introduce previously unseen risk. AI tools access sensitive enterprise data like customer records, proprietary models, internal communications, and even email content, leaving businesses without the right AI safeguards to manage new intrusion techniques and compliance risk. Employees at most businesses are using LLMs – whether their use is sanctioned or not – opening up the risk of sharing confidential data and information.

    Enterprises now face the defining challenge of the remaining decade and beyond: how to harness the power of AI to produce positive business gains while guarding against new and evolving AI-driven security threats.

    Rethinking Security for the AI Era

    In our hyperconnected, AI-driven environment, scale and speed increasingly define both innovation and attack. Threat actors are using AI to automate reconnaissance, generate highly targeted attacks, and exploit vulnerabilities faster than traditional security operations can respond. At the same time, enterprise AI systems themselves – from copilots to autonomous agents – are introducing entirely new attack surfaces.

    The only sustainable response is to rethink how security works. And to use AI to protect against AI

    That means protecting every layer of the AI ecosystem, from employees using AI tools, to applications and agents executing tasks, to the infrastructure powering the next generation of AI workloads.

    At Check Pointour mission is to help customers secure their AI transformation.

    AI is embedded across every application, workflow, and decision. And Check Point secures all of it.

    We are already seeing the emergence of AI-native attacks targeting language interactions, hidden channels, prompt manipulation, and model-level vulnerabilities. These threats cannot be stopped by traditional security tools designed for earlier generations of computing. Preventing them requires AI-native defenses that understand how AI systems operate and how attackers attempt to exploit them.

    Two important announcements at RSAC 2026 underscore how were leading the way in defining what AI security truly is, highlighting what were doing to help our customers and partners move into this new AI-driven future knowing they’re secure with Check Point by their side:

    Introducing the AI Data Center Security Architecture Blueprint

    Our first announcement addresses one of the fastest-growing areas of enterprise investment: private AI infrastructure.

    Organizations around the world are investing hundreds of million of dollars in GPU clusters, model training environments, and inference platforms to power their AI initiatives. These environments, now commonly referred to as AI factories, have quickly become some of the most valuable assets in modern enterprises used in model training and inference. However, they are also some of the most exposed.

    Unlike traditional data centers, AI environments combine high-performance GPU clusters, distributed training pipelines, massive data lakes, and real-time inference APIs. This creates attack surfaces that traditional security architectures were never designed to handle.

    Our new AI Data Center Security Architecture Blueprint helps organizations solve this challenge by providing the industry’s most comprehensive security architecture for protecting AI infrastructure from GPU to gateway. Were securing the infrastructure powering the AI revolution.

    Built in collaboration with NVIDIA and leveraging Check Point’s advanced firewall and AI security technologies, the blueprint delivers defense-in-depth across four critical layers:

    • Perimeter Layer
      Check Point Maestro Hyperscale Firewall provides Zero Trust Network Access (ZTNA), segmentation, and scalable policy enforcement at the entry point to the AI environment
    • Application and LLM Layer
      Check Point WAF with AI Security protects inference APIs and LLM endpoints from prompt injection, data exfiltration, adversarial queries, and API abuse
    • Workload and Container Layer
      Integration with Illumio enables micro-segmentation and east-west traffic control within Kubernetes clusters, preventing lateral movement and isolating compromised containers
    • AI Hardware Layer
      Through a deep partnership with NVIDIA, Check Point security capabilities are embedded directly into NVIDIA BlueField DPUs, delivering high-performance inline inspection without consuming GPU resources.

    We believe AI must be secure by design, embedded across every layer of the AI stack from infrastructure to application.

    Read more about our AI Datacenter Security Architecture Blueprint here.

    Introducing the AI Defense Plane

    Our second announcement brings the full AI security lifecycle into one unified architecture.

    The AI Defense Plane is a comprehensive security framework designed to protect employees, AI applications, and autonomous agents across the enterprise.

    AI has crossed an important threshold and is being used by enterprise businesses for far more than solely generating content. AI systems now connect to tools, access data, and take action on behalf of users. This agentic-driven shift creates an entirely new category of risk.

    Security teams must now govern employee AI usage, monitor AI applications, and secure autonomous agents operating across cloud environments while continuously validating these systems against emerging threats.

    The AI Defense Plane addresses this challenge through a coordinated platform delivering protection across three layers:

    • Workforce AI Security
      Visibility and governance for employee use of AI tools, copilots, and AI-enabled applications. Organizations can discover usage patterns, apply policies, and reduce the risk of data leakage while keeping user experiences seamless
    • AI Application and Agent Security
      Following Check Point’s acquisition of Cyata, the platform expands discovery and observability for AI applications and autonomous agents—helping security teams understand what agents exist, what tools they can access, and what actions they are performing
    • AI Red Teaming
      Now available in controlled availability, cloud-based AI Red Teaming simulates adversarial attacks against AI systems, exposing vulnerabilities in reasoning, workflows, and tool interactions before attackers can exploit them

    These capabilities provide continuous visibility, guardrails, and validation across the entire AI ecosystem.

    Read more about our AI Defense Plane here (link).

    Securing the Future of AI Together

    AI is reshaping how businesses operate, compete, and innovate. The opportunities cannot be understated. But nor can the risks.

    To win in the AI era, enterprises need to build AI security into their AI transformation from the start. From agentic security operations to AI data center protection to the AI Defense Plane, Check Point is pioneering what true AI security looks like – and helping our customers and partners move confidently into this new era with knowledge and confidence.

    The organizations that succeed in the AI era will not just adopt AI faster. They will embrace the right AI security approach from the start.