Category: Health

Core-collapse supernovae are thought to be powered by neutrino-driven energy transport. Now, researchers in Japan have shown that neutrino fast flavor conversion can either enhance or suppress supernova explosions depending on the progenitor star. Using advanced multiangle neutrino radiation hydrodynamics simulations, the team demonstrated that the mass accretion rate is the key factor governing this bifurcated behavior, offering new insight into the evolution and death of massive stars.

Our universe, filled with galaxies and stars, is full of mysteries. Over the centuries, astronomers have observed and documented supernova—the catastrophic explosion of stars—as some of the brightest and most energetic events in the universe. In particular, at the end of their lives, massive stars explode into core-collapse supernovae (CCSNe). Scientists believe these explosions to be mainly facilitated by neutrino-mediated energy transport. However, the effects of collective neutrino oscillations known as fast flavor conversion (FFC) on the CCSN explosion mechanism remain largely unclear. 

Previous studies attempted to investigate the role of FFC in CCSNe using approximate “truncated moment” methods. However, these approaches cannot reliably capture the angular neutrino distributions needed to determine where FFC occurs. 

A new study instead employs a multiangle treatment, allowing the researchers to directly model the angular behavior of neutrinos in momentum space.   

The team of researchers, led by Assistant Professor/Junior Researcher Ryuichiro Akaho from the Faculty of Science and Engineering at Waseda University, Japan, along with co-authors Dr. Hiroki Nagakura from the National Astronomical Observatory of Japan and Professor Shoichi Yamada from Waseda University, has carried out CCSN simulations with multiangle neutrino transport to elucidate the impact of neutrino FFC on CCSNe.Their insightful findings were made available onlineon May 11, 2026, and have been published inVolume 136, Issue 19 ofthe journal Physical Review Letters on May 15, 2026. The paper was also selected as a “Featured in Physics” article by the journal editors, recognizing its significance and broad interest to the physics community.

 In this study, the team combined a quantum kinetic theory-based FFC model with multidimensional Boltzmann neutrino radiation hydrodynamics simulations. Their framework directly identifies where FFC occurs using neutrino angular distributions calculated during the simulation itself. Akaho remarks: “We deploy our first-ever Boltzmann radiation hydrodynamics code that implements an FFC subgrid model, judge the occurrence of FFC directly from angular distributions obtained in simulations, and ascertain neutrino flavor states via physics-based quantum kinetic methodsimplemented through the Bhatnagar-Gross-Krook relaxation scheme. Crucially, we have already demonstrated this extended framework of neutrino transport in our previous work.”

The CCSN simulations presented in this study encompass successful as well as failed explosions, various progenitor models with zero-age main sequence masses of 9, 12, 16, and 20M_⊙, and three different nuclear equations of state (EOSs), namely, variational method-based Furusawa-Togashi EOS, Dirac-Brückner-Hartree-Fock technique, and chiral effective field theory. 

The researchers remarkably found that the impact of FFC on CCSN explosion is bifurcated depending on the progenitors. While FFC promotes shock revival and boosts the explosion energy for the lowest-massprogenitor, it has an inhibitory impact for higher-mass progenitors. The mass accretion rate is the main determinant governing this bifurcated effect. For a high value of mass accretion rate, the contribution of FFC to neutrino heating turns out to be negative,since the concurrent reduction in neutrino luminosity dominates over the enhancement of heating efficiency through FFC-driven spectral hardening of electron-type neutrinos. In contrast, FFC contribution to neutrino heating becomes positive foralow mass accretion rate.

 “Our present results highlight the limitations of approximate neutrino transport and show that a multiangle treatment is essential for accurately capturing FFC effects. Otherwise, important FFC signals may be overlooked or even falsely identified,” highlights Akaho.

Overall, this work provides a robust argument for the involvement of neutrino FFC in the explosion mechanism of CCSNe, improving our understanding of the lifecycle of massive stars and potentially serving as a theoretical guide for future CCSN observations.

 Watchmen, domestic servants, street vendors, auto/cab drivers, security guards, and students are especially invited

Hyderabad, June 3: Lodge Keys No. 297, the city’s primary unit of Freemasonry, will organise a CPR Training Programme on June 6, 2026, from 2:00 PM to 5:30 PM at the Goshamahal Baradari Masonic Building, Goshamahal, in collaboration with GVK Green Health Services (formerly GVK EMRI).

The programme is part of Lodge Keys’ community outreach initiative, “Be a CPR Ambassador”, which aims to train 1,000 citizens in the life-saving skill of Cardiopulmonary Resuscitation (CPR).

CPR is a critical first-aid technique used when a person’s heart stops beating or when breathing ceases. Immediate CPR administered during the “golden minutes” before professional medical help arrives can significantly improve the chances of survival.

Over the past one-and-a-half years, Lodge Keys has successfully trained 758 citizens in CPR free of cost and is now just 242 participants away from achieving its target of 1,000 CPR Ambassadors. In addition, more than 1,400 people have been reached through awareness seminars, and the organisation aims to educate over 10,000 citizens through public awareness programmes eventually.

The June 6 programme will feature hands-on practical training conducted by certified trainers from GVK Green Health Services. Participants will practise CPR on mannequins, enabling them to gain confidence and develop the skills required to respond effectively during emergencies.

In addition to CPR, participants will also receive AED (Automated External Defibrillator) familiarisation training. An AED is a portable device used during sudden cardiac arrest. While CPR helps maintain blood circulation to the brain and other vital organs, an AED can analyse the heart’s rhythm and, when necessary, deliver an electric shock to help restore a normal heartbeat.

The AED module will cover: Recognition of sudden cardiac arrest, Safe operation of an AED, Correct placement of electrode pads, Understanding and following AED voice prompts, When to administer CPR and when to use an AED and How CPR and AED work together to improve survival outcomes

The organisers believe that CPR and AED training should be accessible to all sections of society. Therefore, individuals who can afford the training are requested to contribute a participation fee of ₹1,000. Those who are unable to pay will be accommodated free of cost.

“We do not want the ability to save a life to depend on one’s ability to pay. Anyone willing to learn CPR should have the opportunity to do so,” said the organisers.

Lodge Keys especially invites security guards, watchmen, auto and cab drivers, street vendors, domestic workers, housekeeping staff, students, and other community members to take advantage of this opportunity. Employers and institutions are also encouraged to nominate such individuals for free training.

Participation is limited to 40 persons on a first-come, first-served basis. Prior registration and confirmation are mandatory.

For registration and participation, please contact: D. Ramchandram – 98480 42020; P. Veerabhadrudu – 93910 39047; Arun Selgam – 98491 75197 and G. Ashok Kumar – 94402 26960

Individuals, NGOs, philanthropists, and corporations interested in supporting this life-saving initiative are encouraged to contact D. Ramchandram at 98480 42020 and partner with Lodge Keys to create more CPR Ambassadors.

Mumbai , May 30  : The World Health Organization theme for the World No Tobacco Day 2026 is “Unmasking the Appeal – Countering Nicotine and Tobacco Addiction.” This global campaign aims to raise awareness about the evolving landscape of tobacco and nicotine products, including e-cigarettes, nicotine pouches and synthetic nicotine devices, and how these products may appeal to children and adolescents through flavours, product design and digital social media promotion.

Electronic nicotine delivery products can adversely affect children’s and adolescents’ health by exposing them to nicotine and other harmful substances during critical stages of growth and brain development. Such exposure may affect attention, learning, memory and impulse control, increase the risk of nicotine dependence, and contribute to respiratory and cardiovascular problems. Aerosols from these products may contain substances associated with lung disease and other long-term health risks. Despite decades of progress in tobacco control, newer nicotine products continue to gain visibility through attractive flavours, appealing designs and online promotion. WHO estimates that at least 15 million adolescents aged 13–15 years globally use e-cigarettes, and in countries with available data, children are more likely than adults to vape.

India has been a leader in prohibiting E-cigarettes through the Prohibition of Electronic Cigarettes Act -2019. However, as reported on 21st May 20126 by Press Information Bureau  , Govt. of India, nearly 3 lakh e-cigarettes and vapes worth more than INR 120 crore were seized by the Directorate of Revenue Intelligence  from a smuggling network operating across Maharashtra, Gujarat and other states. 

The LifeFirst Programme, an initiative of Narotam Sekhsaria Foundation in collaboration with Salaam Bombay Foundation, is a tobacco dependence treatment programme working across schools, workplaces, healthcare settings and communities to support tobacco cessation and prevention among adolescents and adults.

As part of its school-based activities this year, LifeFirst sensitized more than 6,000 students in Grades 7 to 9 across 100 schools in Mumbai on the harms associated with tobacco, supari and other harmful products.  During these sessions, e-cigarettes were observed to be used by adolescents, which are available through illegal routes. LifeFirst counsellors also observed that social media exposure, peer influence and perceptions of newer tobacco products as less harmful may contribute to experimentation among young people. Adolescents may perceive them as “cool”, fashionable, harmless or socially acceptable alternatives to conventional tobacco products. However, these products contain addictive nicotine and other potentially harmful substances that may pose health risks.

Protecting children and adolescents from nicotine addiction requires sustained awareness efforts, continued implementation of existing regulations, responsible communication around emerging nicotine products and engagement from parents, schools, communities and public health stakeholders.

On World No Tobacco Day 2026, Narotam Sekhsaria Foundation reiterates the importance of strengthening awareness and preventive efforts for children and adolescents to support healthier future of the country.

New data from AMFM Healthcare reveals a convergence of financial pressure, sleep disruption, and environmental stressors signaling a shift in how Americans experience and manage mental health

ORANGE COUNTY, Calif. (May 28, 2026) – AMFM Healthcare  on Wednesday released findings from a new national survey of 2,000 U.S. adults, revealing that nearly three in four Americans (72.7%) feel stressed on a regular basis, and that many are turning to a mix of healthy, harmful, and emerging digital behaviors to cope.

The survey found that stress is being driven by a convergence of pressures. More than 82.2% of adults say the cost of living is a major source of stress, while 77.1% report that stress has negatively affected their sleep quality. At the same time, 58.5% say feelings of loneliness have increased, reinforcing broader concerns about how mental health challenges are showing up in everyday life.

The data also points to a less commonly discussed, but increasingly relevant, contributor to mental health strain: environmental conditions. More than half of Americans (53.0%) say weather negatively affects their mental health, suggesting that stress is not only emotional and financial, but also shaped by daily surroundings and lived conditions.

“Stress today isn’t coming from one place, it’s layered,” said Ted Guastello, CEO, AMFM Healthcare. “Financial pressure, poor sleep, and loneliness are already taking a toll, and when environmental factors like weather are added in, it helps explain why stress can feel so persistent and difficult to manage.”

The survey also reveals a shift in how Americans are coping. While 69.2% say they use exercise to manage stress, nearly half (46.7%) report using alcohol or cannabis. Meanwhile, 50.8% say social media increases their stress or anxiety, highlighting how some coping behaviors may actually be making stress worse.

One of the most notable findings is the role of technology in emotional coping. Nearly one in three respondents (31.5%) say they have used AI tools or chatbots to cope with stress, reflecting a growing trend as people look for support that is immediate, accessible, and available around the clock.

“We’re seeing people fill gaps in care however they can,” said Guastello. “AI tools are accessible and available 24/7, which makes them appealing, but they’re not a replacement for human care. This reflects a bigger issue: people are looking for support, but the system isn’t always meeting them where they are.”

To better understand whether stress is being experienced differently across the country, the survey findings were also analyzed by region. The results suggest that while stress is widespread nationwide, the factors shaping it, and the ways people experience it, can vary depending on where they live.

In the Midwest, 60.2% say weather affects their mental health, the highest of any region, alongside widespread sleep disruption (76.7%). In the Northeast, stress appears to be more closely tied to isolation, with the highest reported increase in loneliness (60.6%) and a strong share of respondents (59.6%) also citing weather as a factor.

In the South, stress remains closely connected to financial strain, with 73.4% reporting regular stress and 81.6% citing cost of living as a major source of stress. The region also saw the highest share of respondents (52.1%) saying social media contributes to their stress. In the West, economic pressure is even more pronounced, with a nation-leading 84.3% citing cost of living, alongside elevated digital stress (52.0%) and fewer respondents (47.4%) pointing to weather as a factor.

“These regional differences tell an important story,” added Guastello. “Stress may be a national issue, but it doesn’t look exactly the same everywhere. Where people live, how they connect, and what pressures they face all influence how stress shows up, which is why support needs to be flexible, accessible, and responsive to real-life needs.”

Despite widespread need, many Americans still face barriers to care, including cost, long wait times, and stigma, leaving millions to manage stress on their own.

The AMFM Healthcare Local Stress Forecast surveyed adults 18+ across all 50 states to better understand how stress is evolving, and what it will take to address it.

For more information on AMFM Healthcare’s programs, please visit our websites at amfmtreatment.com, missionprephealthcare.com, and missionconnectionhealthcare.com.

MELVILLE, N.Y., May 26 (GLOBE NEWSWIRE) — BioRestorative Therapies, Inc. (“BioRestorative,” “BRTX,” or the “Company”) (Nasdaq:BRTX), a late-stage clinical regenerative medicine company focused on stem cell-based therapies and products, today announced that the last patient has been dosed in its fully enrolled Phase 2 clinical trial evaluating BRTX-100 for the treatment of chronic lumbar disc disease (cLDD), completing treatment administration in the Company’s lead clinical program and advancing the study into the next stage of blinded follow-up ahead of expected topline safety and efficacy data in Q2 2027.

The prospective, randomized, double-blind, sham-controlled, single-disc Phase 2 study enrolled approximately 99 patients across U.S. clinical sites and is designed to evaluate the safety and preliminary efficacy of BRTX-100 in patients with painful chronic lumbar disc disease. Subjects were randomized in a 2:1 ratio to receive either BRTX-100 or control treatment. The primary safety endpoints for the trial include the frequency and severity of adverse events and serious adverse events, as well as imaging-related findings. The primary efficacy responder endpoint is defined as at least a 30% improvement from baseline in both pain — as measured by the Visual Analog Scale — and function –as measured by the Oswestry Disability Index, at week 52. Study follow-up assessments are being conducted at weeks 2, 12, 26, 52 and 104, with MRI evaluations at baseline, week 52 and week 104.

“Completion of dosing in our Phase 2 BRTX-100 trial represents an important transition point for BioRestorative,” said Lance Alstodt, BioRestorative Chief Executive Officer. “We have now completed treatment administration in a rigorously designed, randomized, double-blind, sham-controlled study of our lead regenerative spine candidate, and the program is moving through blinded follow-up toward the 52-week efficacy assessment and expected topline safety and efficacy data in the second quarter of 2027. Importantly, this milestone also comes as we continue Phase 3 readiness activities following our Type B meeting with the FDA, where the agency did not raise clinical safety concerns and provided alignment on key elements of the late-stage development pathway.

“With Phase 2 dosing now complete, we believe BioRestorative is positioned to advance the next phase of BRTX-100 development while reducing expenses and redirecting operational focus and resources toward additional value-creation priorities, including the continued commercialization of our BioCosmeceutical platform,” Mr. Alstodt continued. “Our objective is to build from this milestone with discipline, clinical rigor and a clear focus on advancing our regenerative medicine platform across both therapeutic and commercial opportunities.”

BRTX-100 is BioRestorative’s proprietary autologous, hypoxically cultured mesenchymal stem cell therapy designed for delivery into the harsh, low-oxygen, low-nutrient environment of the intervertebral disc. Patients in the trial received a single intradiscal injection of BRTX-100 consisting of 40 x 10^6 cells administered in approximately 1.5 cc through a minimally invasive outpatient procedure.

Eligible patients enrolled in the study were required to have chronic low back pain persisting for at least six months, failure of conservative therapy for at least six months, MRI-confirmed single symptomatic lumbar disc disease and minimum baseline pain and disability thresholds. Major exclusion criteria included prior lumbar surgery at the index level and prior biologic or cellular disc interventions.

BioRestorative has previously reported favorable blinded safety and preliminary efficacy data from the ongoing Phase 2 trial, including sustained improvements in pain and functional measures across multiple follow-up periods and MRI findings suggestive of potential disc remodeling in certain subjects. In previously disclosed blinded datasets, the Company reported clinically meaningful improvements across pain and function measures, including Visual Analog Scale, Oswestry Disability Index, Roland-Morris Disability Questionnaire and Functional Rating Index assessments. To date, the Company has reported no dose-limiting toxicities or serious adverse events related to BRTX-100 in the safety cohorts evaluated. These blinded findings have been presented at scientific and industry conferences and disclosed through prior Company announcements.

BRTX-100 has received Fast Track designation from the U.S. Food and Drug Administration for the treatment of chronic lumbar disc disease. BioRestorative previously announced a positive outcome from a Type B meeting with the FDA regarding key elements of a potential Phase 3 program and a pathway toward future BLA-enabling activities. The Company expects to continue advancing Phase 3 preparation activities while blinded follow-up in the Phase 2 study continues, with topline safety and efficacy data expected in Q2 2027.

Noida, May 27 : As temperatures soar, Uptown by Advant brings together a vibrant lineup of summer specials, bringing together some of the city’s most loved culinary brands under one roof. Positioned as a one-stop destination for every craving, Uptown by Advant is offering an exciting mix of cooling beverages, indulgent desserts, and seasonal delights designed to help visitors beat the heat in style.

From refreshing coolers and fruit-forward drinks to artisanal shakes and decadent desserts, every corner of Uptown by Advant has something unique to offer this season.

At Chayos, guests can explore an extensive summer menu featuring mango-inspired favourites such as Mango Matcha, Mango Lassi, Mango Shake, Mango Smoothie, and Mango Icy Slush. The brand also introduces refreshing fizzy coolers including Modinagar Shikanji, Lychee Pop Fizz, Strawberry Pop Fizz, Classic Mint Lemonade and Cucumber Mint Lemonade, alongside iced teas and slushies like Kala Khata Iced Tea, Aam Panna Iced Tea and Peach Iced Tea.

For those looking for elevated handcrafted beverages, Rubaru presents a thoughtfully curated seasonal menu featuring Ice Spice, a tender coconut cooler infused with litchi and citrus, Watermelon Basil, and the vibrant Purple Martini, crafted with seasonal jamun and a tangy citrus fizz. Classic summer staples such as Peach Iced Tea, Cucumber Mint Iced Tea, Pineapple Paradise, and Virgin Mojitos add to the refreshing experience.

Mr. Sunil Sharma, Managing Director, Uptown by Advant  said,

“Whether visitors are seeking a quick cool-down, a leisurely café outing, or an evening of indulgence with friends and family, Uptown by Advant offers something for everyone this season. Bringing together diverse culinary experiences in one vibrant destination, it is set to become the go-to hotspot for summer cravings in the city.”

Adding to the lineup, Xero Degrees offers its signature refreshing drinks and crowd-favourite coolers, while Crème Bourne promises indulgence with an irresistible range of waffles, ice creams, and creamy shakes. For classic frozen treats, Baskin Robbins completes the summer experience with its beloved assortment of ice creams and sundaes.

 

 

A fusion dessert combining aromatic rose custard vermicelli with silky coconut pannacotta, garnished with mixed dry fruits and floral notes.

Ingredients

For the Rose Vermicelli Custard:

• Milk – 500 ml

• TATA Sampann Vermicelli – ½ cup

• Custard powder – 2 tbsp

• Sugar – 5–6 tbsp

• Rose syrup or essence – 2–3 tsp syrup or ½ tsp essence

• TATA Sampann Dry fruits & Nut Mix – ¼ cup

• Water or cold milk – 3–4 tbsp

• Ghee (optional) – 1 tsp

For the Coconut Pannacotta:

• Coconut milk – 200 ml

• Gelatin powder – 3 g

• Sugar – 1–2 tbsp

• Cream (optional) – splash

• Salt – pinch

For Garnish (optional):

• Rose petals, extra nuts, or fruit coulis as desired

Method

1. Make the Rose Vermicelli Custard

1. Dissolve custard powder in water or cold milk; mix well to avoid lumps.

2. In a saucepan, bring milk to a gentle boil.

3. If using, heat ghee in a separate pan and lightly roast vermicelli until golden and aromatic.

4. Add roasted vermicelli to the boiling milk and cook until soft.

5. Slowly stir in the dissolved custard mixture while whisking continuously to prevent lumps.

6. Add sugar and rose syrup or essence; simmer until the mixture thickens slightly.

7. Stir in chopped dry fruits.

8. Remove from heat and allow to cool to room temperature. Refrigerate for at least 1–2 hours until chilled.

2. Prepare the Coconut Pannacotta

1. Sprinkle gelatin powder over cold water in a small bowl; let bloom for 5 minutes.

2. In another saucepan, gently warm coconut milk with sugar, cream if using, and salt. Do not let it boil.

3. Remove from heat; add bloomed gelatin and stir until fully dissolved.

4. Pour the mixture into individual ramekins or serving glasses.

5. Cool to room temperature, then refrigerate for 4–6 hours or until set.

3. Assemble & Serve

1. Once both elements are chilled and set, layer rose vermicelli custard over coconut pannacotta in serving glasses or serve side-by-side as desired.

2. Garnish with rose petals, extra dry fruits, or fruit coulis.

3. Serve chilled.

May 26 : Renowned dermatologists Dr Gurveen Waraich Garekar and Dr Siddharth Garekar (popularly known as the Garekars) today announced the official launch of COMPOUND, a skincare brand founded on clinical expertise rather than just endorsement. Moving beyond the “dermatologist-backed” trend, COMPOUND is dermatologist-founded, born directly from the Garekars’ clinical practice to solve the most persistent skin concerns of pigmentation, dullness, and barrier sensitivity through a cohesive, systems-based approach.

In a market saturated with single-ingredient trends, COMPOUND marks a shift toward “Concern-Driven Skincare.” Every formula is engineered to work as part of a collective system, acknowledging that complex issues like melanin formation cannot be treated with isolated actives. 

The “Clinical Gap” – Why COMPOUND Matters

“In our practice, we saw a recurring pattern: patients struggling with pigmentation and sensitised barriers caused by inconsistent routines and the overuse of incompatible actives,” say Dr Gurveen and Dr Siddharth Garekar. “We realised that Indian skin doesn’t need more trends; it needs a steady accumulation of benefits from products designed to work together. COMPOUND is our response as a brand stripped of anything that compromises performance and rooted in long-term skin stability.” 

The Launch Portfolio: The Science of Synergy

COMPOUND debuts with a concentrated lineup of high-performance formulations designed to address pigmentation and dullness at it’s cellular stage:

01 | Pigment Defender Sunscreen

• The Innovation: Specially formulated for Indian skin with 06 new-generation, photostable UV filters with razor sharp focus on UVA protection & not just UVB

• The Purpose: Goes beyond sunburn protection to deliver advanced UVA defense (PA++++), targeting the main cause of persistent skin darkening and deep pigmentation.

• The Texture: Lightweight, fragrance-free, and formulated without oxybenzone or older-generation filters.

02 | Polyactiv10 Serum

• The Innovation: A biomimetic skin repair serum with 10 potent antioxidant actives powered by advanced lipid delivery system.

• The Powerhouse: Features Glow Actives (Niacinamide, 3-O-Ethyl Ascorbic Acid, Licorice, Resveratrol), Barrier Builders (Ceramides NP/EOP, Panthenol, Centella Asiatica), and Hydration Boosters (Sodium Hyaluronate, Beta Glucan, Squalane).

• The Result: An AM/PM multitasker that revives glow, replenishes moisture, and energises tired skin by replicating skin’s natural architecture.

03 | Pigment Corrector Kit (Emulsifier + Booster)

• The Innovation: A first of its kind, two-step pigment correction system- a daily emulsifier paired with twice-weekly resurfacing booster- engineered to block melanin synthesis at every step. 

• The Strategy: One ingredient solves one step. Pigmentation has several. The kit uses a “Compound” effect—addressing pigment synthesis, transfer and turnover in a single protocol. 

• The Result: A calibrated protocol that fades post-acne marks, sun spots, and uneven skin tone- for visibly clearer, more even skin that holds. 

•  COMPOUND prioritises efficacy from formulation to finish. All products are housed in airless packaging to prevent oxidation and maintain the potency of the actives. By focusing on “Systems-Based Skincare,” the brand ensures that each product enhances the next, creating a routine that is greater than the sum of its parts. 

  “Great skincare is not a race to the next trend,” the Garekars conclude. “It is the steady compounding of consistency and compatibility. With COMPOUND, we are bringing the clinical rigour of our dermatology practice directly to the consumer’s vanity.